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Published research indicates that this protection is substantial

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For example, NAD+-dependent enzymes include the sirtuins (SIRT1-7), a family of protein deacetylases involved in gene expression, stress responses, and metabolic regulation, as well as poly(ADP-ribose) polymerases (PARPs) that assist in DNA repair

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Nonetheless, the discovery of this sequence has enabled the laboratory synthesis of this short peptide using a relatively-straightforward chemical process